Originally Posted by Xoanon View Post
I excluded lossless as I was thinking my only options were Lagarith or Huffyuv. But the DNxHD codec sounds like it would be perfect if it creates smaller sizes than the two aforementioned codecs. Any comment on what the best encoder settings to use are?
DNxHD is more of a intermediary format good for editing as every frame is in effect an I-frame, so every frame can be decoded by itself. It uses very similar compression as standard JPEG, MJPEG, and DV. Unlike formats like MPEG2, H.264, H.265, VP9 and so on which are more efficient compression oriented by supporting GOPs, which reduce duplicate image data across 10s-100s of frames. I would suspect that even the PP H.264 encoder would be more efficient than DNxHD, even if the PP H.264 encoder is not as efficient as x264.

Lossless compression would be the best way but if you are going lossy, then there more efficient options out there. Especially if this is just normal 8-bit 4:2:0 YUV stuff, which I'm assuming.