With regards to backing up BluRay DVDs, that depends on what you mean by the word "backup". They can ripped to a hard drive, yes. I'm not aware of anyone having any success reburning them to any format, but you could always go to the Decyrption forum at
http://www.doom9.net
and wade through a lot of stuff to see if maybe somebody has done it. There are no automated rebuilding or reburning tools for BluRay at this time and if anyone has succeeded at burning rips to some kind of disc, it's probably a very intensive manual process.
I have no idea at all if PS3 games can be backed up or what the answer to your hard drive upgrade question is.